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CD69 |
LOCUS ID | 969 | ||||||||||
GENE_SYMBOL | CD69 | ||||||||||
GENE NAME | CD69 molecule | ||||||||||
SYNONYMNS | AIM, EA1, MLR-3, CLEC2C, GP32/28, BL-AC/P26 | ||||||||||
CHROMOSOME | 12 | ||||||||||
HOMOLOGENE ID | 128584 |
microRNAs | NA | NA |
GENE SUMMARY |
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This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit sigls in tural killer cells and platelets. [provided by RefSeq, Aug 2011] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Nephropathy | 1. Neutrophils from DN were faster than neutrophils from either NC or DC to exocytose primary granules with CD69 following initial expression of the adhesion molecule CD11b. | 11749662 |