| CDKAL1 |
| LOCUS ID | 54901 | ||||||||||||||||
| GENE_SYMBOL | CDKAL1 | ||||||||||||||||
| GENE NAME | CDK5 regulatory subu | ||||||||||||||||
| SYNONYMNS | NA | ||||||||||||||||
| CHROMOSOME | 6 | ||||||||||||||||
| HOMOLOGENE ID | 9830 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes. [provided by RefSeq, May 2010] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. JAZF1, FTO, CDKAL1, and HHEX/IDE are associated with diabetic nephropathy. | 23298195 |
| Cardiovascular | 1. WFS1, CDKN2A/B, CDC123/CAMK1D, JAZF1, FTO, CDKAL1, and HHEX/IDE are associated with cardiovascular risk. | 23298195 |
| Retinopathy | 1. CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes. | 28821857 |