| CEACAM1 |
| LOCUS ID | 634 | ||||||||||
| GENE_SYMBOL | CEACAM1 | ||||||||||
| GENE NAME | CEA cell adhesion mo | ||||||||||
| SYNONYMNS | BGP BGP1 BGPI | ||||||||||
| CHROMOSOME | 19 | ||||||||||
| HOMOLOGENE ID | 128630 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequent |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Global Ceacam1 deletion generates a pro-inflammatory state, typically detected in NASH patients, including a Th1 inflammatory phenotype and neutrophilia. | 24258517 |