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CLEC11A |
LOCUS ID | 6320 | ||||||||||
GENE_SYMBOL | CLEC11A | ||||||||||
GENE NAME | C-type lectin domain | ||||||||||
SYNONYMNS | P47, SCGF, LSLCL, CLECSF3 | ||||||||||
CHROMOSOME | 19 | ||||||||||
HOMOLOGENE ID | 2236 |
microRNAs | NA | NA |
GENE SUMMARY |
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This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An altertive splice variant has been described but its biological ture has not been determined. [provided by RefSeq, Jul 2008] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Nephropathy | 1. Deletion of p47 (phox) attenuates diabetes-induced glomerular injury and beta cell dysfunction in the Akita mouse. | 22653270 |