| CNDP2 |
| LOCUS ID | 55748 | ||||||||||
| GENE_SYMBOL | CNDP2 | ||||||||||
| GENE NAME | CNDP dipeptidase 2 ( | ||||||||||
| SYNONYMNS | CN2, CPGL, PEPA, HsT2298, HEL-S-13 | ||||||||||
| CHROMOSOME | 18 | ||||||||||
| HOMOLOGENE ID | 10085 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| CNDP2, also known as tissue carnosise and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosise (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Haplotype including these SNPs (C-C-G) was associated with a threefold increased risk of diabetic nephropathy (OR 2. 98, 95% CI 2. 43-3. 67, p < 0.0001). These data suggest that common variants in CNDP1 and CNDP2 play a role in susceptibility to kidney disease in patients with type 2 diabetes. | 21573905 |