| CORO1A |
| LOCUS ID | 11151 | ||||||||||
| GENE_SYMBOL | CORO1A | ||||||||||
| GENE NAME | coronin 1A | ||||||||||
| SYNONYMNS | p57, IMD8, TACO, CLABP, HCORO1, CLIPINA | ||||||||||
| CHROMOSOME | 16 | ||||||||||
| HOMOLOGENE ID | 6545 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudo |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Tuberculosis | 1. Repression of RXR gene could hamper VDR-RXR heterodimer formation and thus would up regulate TACO gene expression which may predispose the type-2 DM patients to tuberculosis. | 26089620 |