| Complication | Evidence | PMID |
| Nephropathy | 1. Elevated serum MBL in T2DM patients indicated a possible poor diabetic control and bad progression of the disease with possibility of the presence, or development of diabetic nephropathy especially incombination with elevated serum CRP. | 21858386 |
| Cardiovascular | 1. Our findings emphasize that diabetics were 5.6 times more likely to have high CRP levels than nondiabetics; as CRP is a predictor of cardiovascular disease risk, it can be recognized that diabetics are at more risk of cardiovascular disease than nondiabetics. | 26379442 |
| Retinopathy | 1. The serum ischemia modified albumin (IMA) and hs-CRP concentration were significantly high in DR patients, and were positively associated with the seriousness of DR, which may contribute to the development of DR. 2. The results obtained in the present study indicate that type 2 diabetic patients with higher levels of CRP, TNF- alpha and VEGF were likely to develop diabetic retinopathy, with significant association found in patients with proliferative diabetic retinopathy. | 20137285 |
| Atherosclerosis | 1. Serum hs-CRP levels on admission in patients with acute coronary syndrome (ACS) could predict the severity and complexity of coronary atherosclerosis together with multivessel disease, LVEF, and troponin levels. | 26118590 |
| Neuropathy | 1. High levels of C-reactive protein and interleukin (IL)-6 were most consistently associated with diabetic polyneuropathy, high MNSI score, and specific neuropathic deficits, whereas some inverse associations were seen for IL-18. This study shows that subclinical inflammation is associated with diabetic polyneuropathy and neuropathic impairments. This association appears rather specific because only certain immune mediators and impairments are involved. | 26118590 |
| Dyslipidemia | 1. The high prevalence of obesity among diabetics, together with elevated levels of triglycerides and CRP, suggest coexistence of dyslipidemia and inflammation in diabetes. | 26118590 |
| Insulin resistance and inflammation | 1. CRP and IL-2 may represent two important effectors in the early inflammatory events in obese individuals without co-morbidities. | 19131463 |
