CST2
LOCUS ID1470
GENE_SYMBOLCST2
GENE NAME cystatin SA
SYNONYMNSNA
CHROMOSOME20
HOMOLOGENE ID88653
microRNAsNANA
GENE SUMMARY
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. Serum cystatin SA level could reflect kidney function and thus may serve as a biomarker for DN and other forms of nephropathy31174096