| CXCL11 |
| LOCUS ID | 6373 | ||||||||||
| GENE_SYMBOL | CXCL11 | ||||||||||
| GENE NAME | chemokine (C-X-C mot | ||||||||||
| SYNONYMNS | IP9, H174, IP-9, b-R1, I-TAC, SCYB11, SCYB9B | ||||||||||
| CHROMOSOME | 4 | ||||||||||
| HOMOLOGENE ID | 3944 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokin |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Urinary mRNA levels of CXCL10 and CXCL11 are decreased, and those of collagen I A1 chain and fibronectin are increased in diabetic nephropathy. | 25865428 |