CXCL14
LOCUS ID9547
GENE_SYMBOLCXCL14
GENE NAMEC-X-C motif chemokin
SYNONYMNSKEC KS1 BMAC BRAK NJAC MIP2G MIP-2g SCYB14
CHROMOSOME5
HOMOLOGENE ID3592
microRNAsNANA
GENE SUMMARY
This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated th

OBSERVATIONS

Complication Evidence PMID
Insulin resistance and inflammation1. CXCL14 expression is elevated in white adipose tissue (WAT) of high-fat diet (HFD)-fed obese mice and leptin-system defective mutant mice. 19251036