| DAPK2 |
| LOCUS ID | 23604 | ||||||||||
| GENE_SYMBOL | DAPK2 | ||||||||||
| GENE NAME | death associated pro | ||||||||||
| SYNONYMNS | DRP1 DRP-1 | ||||||||||
| CHROMOSOME | 15 | ||||||||||
| HOMOLOGENE ID | 74940 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. DAPK2 mRNA is also downregulated in high-fat diet-induced obese mice. | 26038578 |