EXOSC7
LOCUS ID23016
GENE_SYMBOLEXOSC7
GENE NAMEexosome component 7
SYNONYMNSp8, EAP1, RRP42, Rrp42p, hRrp42p
CHROMOSOME3
HOMOLOGENE ID8994
microRNAsNANA
GENE SUMMARY
EXOSC7 (Exosome Component 7) is a Protein Coding gene. Diseases associated with EXOSC7 include X-Linked Nephrolithiasis Type I. Among its related pathways are Metabolism of proteins and PERK regulates gene expression. Gene Ontology (GO) annotations related to this gene include RNA binding and exoribonuclease activity. An important paralog of this gene is EXOSC8.

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. p8 is also induced in diabetic kidney. Small interfering R (siR)-mediated R interference indicates that p8 is required for endothelin-induced hypertrophy. Thus, p8 is a novel marker for diabetic renal hypertrophy.12374743