| FABP1 |
| LOCUS ID | 2168 | |||||||||||||
| GENE_SYMBOL | FABP1 | |||||||||||||
| GENE NAME | fatty acid binding p | |||||||||||||
| SYNONYMNS | FABPL, L-FABP | |||||||||||||
| CHROMOSOME | 2 | |||||||||||||
| HOMOLOGENE ID | 1106 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. L-FABP is an independent predictor of progression of DN irrespective of disease stage. | 23378622 |
| Cardiovascular | 1. Irrespective of diabetes, high urinary L-FABP correlated with the development of ESRD and CVD. | 26189083 |