| FBXO8 |
| LOCUS ID | 26269 | ||||||||||
| GENE_SYMBOL | FBXO8 | ||||||||||
| GENE NAME | F-box protein 8 | ||||||||||
| SYNONYMNS | FBS, DC10, FBX8 | ||||||||||
| CHROMOSOME | 4 | ||||||||||
| HOMOLOGENE ID | 8137 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitition. The F-box proteins are divided into 3 classesFbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modul |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Retinopathy | 1. It was concluded that thecombination of HbA1 and FBS levels will be useful for long-term control of diabetes and of progression of retinopathy. | 6855017 |