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FFAR4 |
LOCUS ID | 338557 | ||||||||||
GENE_SYMBOL | FFAR4 | ||||||||||
GENE NAME | free fatty acid rece | ||||||||||
SYNONYMNS | GT01 PGR4 BMIQ10 GPR120 GPR129 O3FAR1 | ||||||||||
CHROMOSOME | 10 | ||||||||||
HOMOLOGENE ID | 18769 |
microRNAs | NA | NA |
GENE SUMMARY |
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This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Insulin resistance and inflammation | 1. It has been shown that stimulation of ?3-FA (omega-3 fatty acids) to FFAR4 is followed by receptor phosphorylation. | 25076939 |