| FITM2 |
| LOCUS ID | 128486 | ||||||||||
| GENE_SYMBOL | FITM2 | ||||||||||
| GENE NAME | fat storage inducing | ||||||||||
| SYNONYMNS | Fit2 SIDDIS C20orf142 dJ881L22.2 | ||||||||||
| CHROMOSOME | 20 | ||||||||||
| HOMOLOGENE ID | 35254 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| FIT2 belongs to an evolutionarily conserved family of proteins involved in fat storage (Kadereit et al., 2008 [PubMed 18160536]).[supplied by OMIM, May 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Mice with adipose tissue (AT)-specific FIT2 knockout exhibited lipodystrophic features, with reduced AT mass, insulin resistance, and greater inflammation in AT when fed a high-fat diet. | 30020828 |