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GAS1 |
LOCUS ID | 2619 | ||||||||||
GENE_SYMBOL | GAS1 | ||||||||||
GENE NAME | growth arrest-specif | ||||||||||
SYNONYMNS | NA | ||||||||||
CHROMOSOME | 9 | ||||||||||
HOMOLOGENE ID | 1548 |
microRNAs | NA | NA |
GENE SUMMARY |
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Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Nephropathy | 1.MiRNA-34a regulated mesangial proliferation and glomerular hypertrophy by directly inhibiting GAS1 in early DN. | 23298195 |