| GFPT1 |
| LOCUS ID | 2673 | ||||||||||
| GENE_SYMBOL | GFPT1 | ||||||||||
| GENE NAME | glutamine--fructose- | ||||||||||
| SYNONYMNS | GFA, GFAT, GFPT, MSLG, CMS12, GFAT1, CMSTA1, GFAT, 1, GFAT1m, GFPT1L | ||||||||||
| CHROMOSOME | 2 | ||||||||||
| HOMOLOGENE ID | 68220 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Nephropathy | 1. Genetic variation in GFPT1 is thus unlikely to have a major impact on susceptibility to diabetic nephropathy. | 14988277 |