| GSTP1 |
| LOCUS ID | 2950 | ||||||||||
| GENE_SYMBOL | GSTP1 | ||||||||||
| GENE NAME | glutathione S-transf | ||||||||||
| SYNONYMNS | PI DFN7, GST3, GSTP, FAEES3, HEL-S-22 | ||||||||||
| CHROMOSOME | 11 | ||||||||||
| HOMOLOGENE ID | 660 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xeno |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. No association of SNP 313A?G in GSTP1 with nephropathy, hypertension and dyslipidemia in type 2 diabetes mellitus. | 30883298 |