| HCN2 |
| LOCUS ID | 610 | ||||||||||
| GENE_SYMBOL | HCN2 | ||||||||||
| GENE NAME | hyperpolarization ac | ||||||||||
| SYNONYMNS | BCNG2, HAC-1, BCNG-2 | ||||||||||
| CHROMOSOME | 19 | ||||||||||
| HOMOLOGENE ID | 31022 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain.[supplied by OMIM, Jul 2010] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Neuropathy | 1. These indicate that diabetes induces the overexpression of HCN channels and the electrophysiological changes of HCN currents in the A- and C-fiber nodose neurons, which might contribute to the diabetes-induced alteration of cell excitability in the vagal afferent neurons. | 19815055 |