| HS6ST3 |
| LOCUS ID | 266722 | ||||||||||
| GENE_SYMBOL | HS6ST3 | ||||||||||
| GENE NAME | heparan sulfate 6-O- | ||||||||||
| SYNONYMNS | |||||||||||
| CHROMOSOME | 13 | ||||||||||
| HOMOLOGENE ID | 89201 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000 [PubMed 10644753]).[supplied by OMIM, Mar 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Retinopathy | 1. The heparan sulfate 6-O-sulfotransferase 3 (HS6ST3) gene is involved in heparan sulphate and heparin metabolism, and has been reported to be associated with diabetic retinopathy in type 2 diabetes | 24371161 |