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IGFBP5 |
LOCUS ID | 3488 | ||||||||||
GENE_SYMBOL | IGFBP5 | ||||||||||
GENE NAME | insulin like growth | ||||||||||
SYNONYMNS | IBP5 | ||||||||||
CHROMOSOME | 2 | ||||||||||
HOMOLOGENE ID | 56489 |
microRNAs | NA | NA |
GENE SUMMARY |
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IGFBP5 (Insulin Like Growth Factor Binding Protein 5) is a Protein Coding gene. Diseases associated with IGFBP5 include Insulin-Like Growth Factor I and Renal Osteodystrophy. Among its related pathways are Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include fibronectin binding and insulin-like growth factor I binding. An important paralog of this gene is IGFBP3. |
OBSERVATIONS |
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Complication | Evidence | PMID |
Neuropathy | 1. Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy. | 26025657 |