| IL17F |
| LOCUS ID | 112744 | ||||||||||
| GENE_SYMBOL | IL17F | ||||||||||
| GENE NAME | interleukin 17F | ||||||||||
| SYNONYMNS | ML1, ML-1, CANDF6, IL-17F | ||||||||||
| CHROMOSOME | 6 | ||||||||||
| HOMOLOGENE ID | 17115 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Tuberculosis | 1. In persons with DM or pre-DM, latent infection is characterized by diminished circulating levels of type 1 (interferon ?, interleukin 2, and tumor necrosis factor ?) and type 17 (interleukin 17F) cytokines. | 24907382 |