| IL22 |
| LOCUS ID | 50616 | ||||||||||
| GENE_SYMBOL | IL22 | ||||||||||
| GENE NAME | interleukin 22 | ||||||||||
| SYNONYMNS | TIFa IL-21 IL-22 ILTIF IL-TIF IL-D110 zcyto18 TIFIL-23 | ||||||||||
| CHROMOSOME | 12 | ||||||||||
| HOMOLOGENE ID | 9669 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. [provided by RefSeq, Jul 2018] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. A specific enrichment of IL-17- and IL-22-producing CD4(+) T cells was found in adipose tissue of type 2 diabetic obese patients. | 24520123 |