| IL34 |
| LOCUS ID | 146433 | ||||||||||
| GENE_SYMBOL | IL34 | ||||||||||
| GENE NAME | interleukin 34 | ||||||||||
| SYNONYMNS | IL-34 C16orf77 | ||||||||||
| CHROMOSOME | 16 | ||||||||||
| HOMOLOGENE ID | 12648 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. IL-34 plays a crucial role in the development of GDM by targeting CSF-1R, insulin production and ? cell function. | 31648183 |