| IRF2BP2 |
| LOCUS ID | 359948 | ||||||||||
| GENE_SYMBOL | IRF2BP2 | ||||||||||
| GENE NAME | interferon regulator | ||||||||||
| SYNONYMNS | CVID14 | ||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 34290 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. IRF2BP2 is an integrative restrainer in controlling hepatic steatosis, insulin resistance and inflammation in NAFLD through transcriptionally repressing ATF3 gene expression. | 31529495 |