| KLF15 |
| LOCUS ID | 28999 | ||||||||||
| GENE_SYMBOL | KLF15 | ||||||||||
| GENE NAME | Kruppel like factor | ||||||||||
| SYNONYMNS | KKLF | ||||||||||
| CHROMOSOME | 3 | ||||||||||
| HOMOLOGENE ID | 8553 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Mice with a targeted deletion of KLF15 exhibit increased hepatic ER stress, inflammation, and JNK activation compared to WT mice; however, KLF15 (-/-) mice are protected against hepatic insulin resistance and fatty liver under high-fat feeding conditions and in response to pharmacological induction of ER stress. | 24167585 |