| LAP3 |
| LOCUS ID | 51056 | ||||||||||
| GENE_SYMBOL | LAP3 | ||||||||||
| GENE NAME | leucine aminopeptida | ||||||||||
| SYNONYMNS | LAP, PEPS, LAPEP, HEL-S-106 | ||||||||||
| CHROMOSOME | 4 | ||||||||||
| HOMOLOGENE ID | 41072 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| LAP3 (Leucine Aminopeptidase 3) is a Protein Coding gene. Diseases associated with LAP3 include Bacterial Vaginosis and Trichomoniasis. Among its related pathways are Arginine and proline metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include peptidase activity and aminopeptidase activity. An important paralog of this gene is NPEPL1. |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. NAG reflects lysosomal dysfunction of both glomerular and proximal tubular epithelial cells, which may be caused by poor glycemic control, and that ALP, LAP, and gamma-GTP reflect brush border damage of proximal tubules, which may be caused by diabetic nephropathy. | 1685160 |