| LTB4R2 |
| LOCUS ID | 56413 | ||||||||||
| GENE_SYMBOL | LTB4R2 | ||||||||||
| GENE NAME | leukotriene B4 recep | ||||||||||
| SYNONYMNS | BLT2, NOP9, BLTR2, JULF2, KPG_004, LTB4-R2, LTB4-R, 2 | ||||||||||
| CHROMOSOME | 14 | ||||||||||
| HOMOLOGENE ID | 10519 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| LTB4R2 (Leukotriene B4 Receptor 2) is a Protein Coding gene. Diseases associated with LTB4R2 include Diffuse Pulmonary Fibrosis. Among its related pathways are Calcium signaling pathway and Eicosanoid ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and leukotriene B4 receptor activity. An important paralog of this gene is LTB4R. |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Retinopathy | 1. Transcellular delivery of LTA(4) from marrow-derived cells to retinal cells in the generation of LTB(4) and the death of endothelial cells and, thus, might contribute to chronic inflammation and retinopathy in diabetes. | 19834040 |