LTB4R2
LOCUS ID56413
GENE_SYMBOLLTB4R2
GENE NAMEleukotriene B4 recep
SYNONYMNSBLT2, NOP9, BLTR2, JULF2, KPG_004, LTB4-R2, LTB4-R, 2
CHROMOSOME14
HOMOLOGENE ID10519
microRNAsNANA
GENE SUMMARY
LTB4R2 (Leukotriene B4 Receptor 2) is a Protein Coding gene. Diseases associated with LTB4R2 include Diffuse Pulmonary Fibrosis. Among its related pathways are Calcium signaling pathway and Eicosanoid ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and leukotriene B4 receptor activity. An important paralog of this gene is LTB4R.

OBSERVATIONS

Complication Evidence PMID
Retinopathy1. Transcellular delivery of LTA(4) from marrow-derived cells to retinal cells in the generation of LTB(4) and the death of endothelial cells and, thus, might contribute to chronic inflammation and retinopathy in diabetes.19834040