| MACROD2 |
| LOCUS ID | 140733 | ||||||||||
| GENE_SYMBOL | MACROD2 | ||||||||||
| GENE NAME | mono-ADP ribosylhydr | ||||||||||
| SYNONYMNS | C2orf133 C20orf133 | ||||||||||
| CHROMOSOME | 20 | ||||||||||
| HOMOLOGENE ID | 85987 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage. [provided by RefSeq, May 2017] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. CONCLUSION:MACROD2 is a potential genetic determinant of serum VAP-1 levels, probably through transcriptional regulation of adipogenesis. | 29364582 |