| MBL3P |
| LOCUS ID | 50639 | |||||||||||||
| GENE_SYMBOL | MBL3P | |||||||||||||
| GENE NAME | mannose-binding lect | |||||||||||||
| SYNONYMNS | MBL, COLEC2 | |||||||||||||
| CHROMOSOME | 10 | |||||||||||||
| HOMOLOGENE ID | 0 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| MBL3P (Mannose-Binding Lectin Family Member 3, Pseudogene) is a Pseudogene. Diseases associated with MBL3P include Mannose-Binding Lectin Deficiency and Coccidioidomycosis. |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Cardiovascular | 1. In type 2 diabetic South Asians, the O/O MBL genotype is associated with cardiovascular events, although single serum MBL levels are not. 2. In the general population, low serum MBL levels are associated with higher risk of infection, type 2 diabetes, autoimmune and cardiovascular disease. | 21729275 |
| Retinopathy | 1. MBL is a novel, independent diagnostic marker of DR in type 2 diabetic patients, suggesting that MBL may be involved in the pathogenesis of DR in diabetic patients. | 26136138 |