| MCAM |
| LOCUS ID | 4162 | ||||||||||
| GENE_SYMBOL | MCAM | ||||||||||
| GENE NAME | melanoma cell adhesi | ||||||||||
| SYNONYMNS | CD146, MUC18 | ||||||||||
| CHROMOSOME | 11 | ||||||||||
| HOMOLOGENE ID | 4742 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| MCAM (Melanoma Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with MCAM include Noonan Syndrome-Like Disorder With Or Without Juvenile Myelomonocytic Leukemia and Melanoma. Among its related pathways are Adhesion and Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. An important paralog of this gene is BCAM. |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Expression of CD146 and P-selectin in patients with type 2 diabetes is elevated, and they are positively correlated with severity of diabetic nephropathy. | 22088599 |