| MRPL28 |
| LOCUS ID | 10573 | ||||||||||
| GENE_SYMBOL | MRPL28 | ||||||||||
| GENE NAME | mitochondrial riboso | ||||||||||
| SYNONYMNS | p15, MAAT1 | ||||||||||
| CHROMOSOME | 16 | ||||||||||
| HOMOLOGENE ID | 4693 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rR composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rR. Among different species, the proteins compris |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Retinopathy | 1. HLA-A24 is not a protective factor for Proliferative diabetic retinopathy (PDR), but is a risk factor of its development. | 18040918 |