| NLRX1 |
| LOCUS ID | 79671 | ||||||||||
| GENE_SYMBOL | NLRX1 | ||||||||||
| GENE NAME | NLR family member X1 | ||||||||||
| SYNONYMNS | NOD5 NOD9 NOD26 DLNB26 CLR11.3 | ||||||||||
| CHROMOSOME | 11 | ||||||||||
| HOMOLOGENE ID | 11623 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The protein encoded by this gene is a member of the NLR family and localizes to the outer mitochondrial membrane. The encoded protein is a regulator of mitochondrial antivirus responses. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2013] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. While mitochondrial content was equal, NLRX1 loss in hepatocytes leads to increased fatty acid oxidation and decreased steatosis. | 29514047 |