NME2
LOCUS ID4831
GENE_SYMBOLNME2
GENE NAMENME/NM23 nucleoside
SYNONYMNSPUF, NDKB, NDPKB, NM23B, NDPK-B, NM23-H2
CHROMOSOME17
HOMOLOGENE ID133879
microRNAsNANA
GENE SUMMARY
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple altertively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates turally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010]

OBSERVATIONS

Complication Evidence PMID
Retinopathy1. Our data identify NDPKB as a protective factor in the retina, which controls Ang2 expression and the hexosamine pathway.25900369