| NOX1 |
| LOCUS ID | 27035 | ||||||||||
| GENE_SYMBOL | NOX1 | ||||||||||
| GENE NAME | DPH oxidase 1 | ||||||||||
| SYNONYMNS | MOX1, NOH1, NOH-1, GP91-2 | ||||||||||
| CHROMOSOME | X | ||||||||||
| HOMOLOGENE ID | 48495 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of the DPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Altertively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Potential candidate genes in these regions that have been implicated in diabetic nephropathy and/or renal damage in models of hypertension include CYBA (or P22PHOX) (16q24), NOX1 (10q22), and NOX3 (6q25.1-q26) | 17336700 |