| NR2E1 |
| LOCUS ID | 7101 | ||||||||||
| GENE_SYMBOL | NR2E1 | ||||||||||
| GENE NAME | nuclear receptor sub | ||||||||||
| SYNONYMNS | TLL TLX XTLL | ||||||||||
| CHROMOSOME | 6 | ||||||||||
| HOMOLOGENE ID | 37750 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The protein encoded by this gene is an orphan receptor involved in retinal development. The encoded protein also regulates adult neural stem cell proliferation and may be involved in control of aggressive behavior. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Glucose and palmitate treatment significantly increased NR2E1 gene expression and inflammatory cytokines production in PBMCs in vitro. | 25813674 |