| NR5A2 |
| LOCUS ID | 2494 | ||||||||||
| GENE_SYMBOL | NR5A2 | ||||||||||
| GENE NAME | nuclear receptor sub | ||||||||||
| SYNONYMNS | B1F CPF FTF B1F2 LRH1 LRH-1 FTZ-F1 hB1F-2 FTZ-F1beta | ||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 20827 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development. [provided by RefSeq, Jun 2016] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. The associations of the ABO blood group gene and NR5A2 gene variants with PC discovered by recent genome-wide association studies may link insulin resistance, inflammation, and thrombosis to pancreatic carcinogenesis. | 20647474 |