| NRIP1 |
| LOCUS ID | 8204 | ||||||||||
| GENE_SYMBOL | NRIP1 | ||||||||||
| GENE NAME | nuclear receptor int | ||||||||||
| SYNONYMNS | CAKUT3 RIP140 | ||||||||||
| CHROMOSOME | 21 | ||||||||||
| HOMOLOGENE ID | 2606 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Overexpression of RIP140 in macrophages results in M1?like polarization and expansion during the inflammatory response. | 28586037 |