| P2RX2 |
| LOCUS ID | 22953 | ||||||||||
| GENE_SYMBOL | P2RX2 | ||||||||||
| GENE NAME | purinergic receptor | ||||||||||
| SYNONYMNS | P2X2, DF41 | ||||||||||
| CHROMOSOME | 12 | ||||||||||
| HOMOLOGENE ID | 14251 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates syptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Neuropathy | 1. Purinergic receptor signaling transduction pathways might become potential targets for treatment for painful DPN. | 23090494 |