| PDHX |
| LOCUS ID | 8050 | ||||||||||
| GENE_SYMBOL | PDHX | ||||||||||
| GENE NAME | pyruvate dehydrogena | ||||||||||
| SYNONYMNS | E3BP, OPDX, PDX1, proX, DLDBP | ||||||||||
| CHROMOSOME | 11 | ||||||||||
| HOMOLOGENE ID | 55757 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This pr |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Retinopathy | 1. Measurement of serum PZ levels in diabetic pregnancy might help to predict the risk of progressive retinopathy. | 1962518 |