| PECAM1 |
| LOCUS ID | 5175 | ||||||||||
| GENE_SYMBOL | PECAM1 | ||||||||||
| GENE NAME | platelet and endothe | ||||||||||
| SYNONYMNS | CD31, PECA1, GPIIA', PECAM-1, endoCAM, CD31/EndoCAM | ||||||||||
| CHROMOSOME | 17 | ||||||||||
| HOMOLOGENE ID | 47925 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Neuropathy | 1. CD34+KDR+ and CD31+133+ EPC differentiation could have a prognostic and therapeutic significance in the healing process of neuropathic and neuroischemic lesions. | 24624298 |