| PLEKHH2 |
| LOCUS ID | 130271 | ||||||||||
| GENE_SYMBOL | PLEKHH2 | ||||||||||
| GENE NAME | pleckstrin homology | ||||||||||
| SYNONYMNS | PLEKHH1L | ||||||||||
| CHROMOSOME | 2 | ||||||||||
| HOMOLOGENE ID | 35317 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| PLEKHH2 (Pleckstrin Homology, MyTH4 And FERM Domain Containing H2) is a Protein Coding gene. Diseases associated with PLEKHH2 include Focal Segmental Glomerulosclerosis. Gene Ontology (GO) annotations related to this gene include identical protein binding and actin binding. An important paralog of this gene is PLEKHH1. |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Nephropathy | 1. These findings suggest that PLEKHH2, which has mRNA and protein expression exclusively in the glomerulus, may be a genetic risk factor for susceptibility to DN in the GoKinD population. | 22128263 |