| PLXDC2 |
| LOCUS ID | 84898 | ||||||||||
| GENE_SYMBOL | PLXDC2 | ||||||||||
| GENE NAME | plexin domain contai | ||||||||||
| SYNONYMNS | TEM7R | ||||||||||
| CHROMOSOME | 10 | ||||||||||
| HOMOLOGENE ID | 41666 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| PLXDC2 (Plexin Domain Containing 2) is a Protein Coding gene. Diseases associated with PLXDC2 include Vulva Cancer and Vulva Squamous Cell Carcinoma. An important paralog of this gene is PLXDC1. |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Retinopathy | 1. The SNPs rs9362054 near the CEP162 gene and rs4462262 near the UBE2D1 gene were associated with DR (OR = 1.66, p = 0.001; OR = 1.37, p = 0.031; respectively), and rs12219125 near the PLXDC2 gene was associated (suggestive) with CAD (OR = 2.26, p = 0.034). Furthermore, rs9362054 near the CEP162 gene was significantly associated with both complications (OR = 2.27, p = 0.0021). | 31130920 |