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PODN |
LOCUS ID | 127435 | ||||||||||
GENE_SYMBOL | PODN | ||||||||||
GENE NAME | podocan | ||||||||||
SYNONYMNS | PCAN, SLRR5A | ||||||||||
CHROMOSOME | 1 | ||||||||||
HOMOLOGENE ID | 17803 |
microRNAs | NA | NA |
GENE SUMMARY |
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The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury. [provided by RefSeq, Jul 2016] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Nephropathy | 1. Results suggest that podocan is involved in kidney function and could be a unique therapeutic target for diabetic nephropathy. | 29264529 |