| PPY |
| LOCUS ID | 5539 | ||||||||||
| GENE_SYMBOL | PPY | ||||||||||
| GENE NAME | pancreatic polypepti | ||||||||||
| SYNONYMNS | PP, PNP | ||||||||||
| CHROMOSOME | 17 | ||||||||||
| HOMOLOGENE ID | 2039 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestil functions and may be important in the regulation of food intake. Plasma level of this hormone has been sho |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Neuropathy | 1. Measuring PP serum levels in diabetics after a protein rich meal can be useful to check vagus nerve function in the gastrointestil tract in order to detect autonomic neuropathy. | 7739457 |