| RBP1 |
| LOCUS ID | 5947 | ||||||||||
| GENE_SYMBOL | RBP1 | ||||||||||
| GENE NAME | retinol binding prot | ||||||||||
| SYNONYMNS | CRBP, RBPC, CRBP1, CRBPI, CRABP-I | ||||||||||
| CHROMOSOME | 3 | ||||||||||
| HOMOLOGENE ID | 2175 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Retinopathy | 1. Approximately 48 and 61 spots were identified in control and diabetic retinopathy respectively, of which three protein spots RBP1 (retinol-binding protein 1), NUD10 (Diphosphoinositol polyphosphohydrolase 3 alpha), NGB (neuroglobin) were down regulated and HBG2 (hemoglobin) and BY55 (CD 160 antigen) were upregulated in diabetic retinopathy. | 26129748 |