| REG1A |
| LOCUS ID | 5967 | ||||||||||
| GENE_SYMBOL | REG1A | ||||||||||
| GENE NAME | regenerating islet-d | ||||||||||
| SYNONYMNS | P19, PSP, PTP, REG, ICRF, PSPS, PSPS1 | ||||||||||
| CHROMOSOME | 2 | ||||||||||
| HOMOLOGENE ID | 68282 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Urinary PSP excretion was increased from the initial stage of diabetic nephropathy and this increase became more marked as nephropathy progressed. | 9678681 |