| RGS10 |
| LOCUS ID | 6001 | ||||||||||
| GENE_SYMBOL | RGS10 | ||||||||||
| GENE NAME | regulator of G prote | ||||||||||
| SYNONYMNS | |||||||||||
| CHROMOSOME | 10 | ||||||||||
| HOMOLOGENE ID | 37710 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associ |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Regulator of G-protein signaling-10 (RGS10) protein is a negative modulator of the inflammatory response in macrophages and microglia. | 30032988 |