| ROMO1 |
| LOCUS ID | 140823 | ||||||||||
| GENE_SYMBOL | ROMO1 | ||||||||||
| GENE NAME | reactive oxygen spec | ||||||||||
| SYNONYMNS | MTGM, MTGMP, C20orf52, bA353C18.2 | ||||||||||
| CHROMOSOME | 20 | ||||||||||
| HOMOLOGENE ID | 7096 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The protein encoded by this gene is a mitochondrial membrane protein that is responsible for increasing the level of reactive oxygen species (ROS) in cells. The protein also has antimicrobial activity against a variety of bacteria by inducing bacterial membrane breakage. [provided by RefSeq, Nov 2014] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Retinopathy | 1. The rs6060566 polymorphism of the Romo-1 gene was found to be an independent risk factor for DR in Caucasians with T2DM. | 25824963 |